Structura

Biotechnology

We are unlocking the potential of cryo-electron microscopy (cryo-EM) as a high-throughput structure determination technique for life sciences and drug discovery.

GPCR

About

Cryo-EM is a recent Nobel Prize-winning technique for microscopy and 3D reconstruction of proteins and other biological molecules. A sample containing proteins and protein-ligand complexes is frozen in a thin film of ice and subsequently imaged in an electron microscope. The resulting microscopy data is analyzed via complex algorithms to identify the contents of the sample and solve the 3D atomic structures of the embedded protein molecules in their near-native states.

cryoSPARC

Structura Bio's state-of-the-art cryoSPARC™ platform is used globally for cryo-EM data analysis and 3D reconstruction. CryoSPARC offers specially designed, proprietary algorithms for membrane proteins, ion channels, GPCRs and drug targets with ligands bound.

Milestones

Novel technologies and algorithms applied to the cryo-EM field
2015
Building Proteins in a Day

Scientific paper describing efficient 3D molecular structure estimation accelerated with GPUs.

2017
cryoSPARC™ Released

Ab-initio reconstruction and rapid, high-resolution refinement released in cryoSPARC along with our Nature Methods paper.

2018
CryoSPARC v2

Used by over 400 institutions, cryoSPARC v2 is a full-pipeline package for single-particle reconstruction.

2019
CryoSPARC Live

The ability to resolve high-resolution structures in real-time during data collection at the microscope.

400+
Institutions using cryoSPARC
40+
Countries
400+
Citations
1M+
Jobs run in cryoSPARC

Our Team

Ali Punjani

Ali Punjani

Co-Founder & CEO
Saara Virani

Saara Virani

Chief Operating Officer
Suhail Dawood

Suhail Dawood

Chief Product Officer
Stephan Arulthasan

Stephan Arulthasan

Senior Software Engineer
Nick Frasser

Nick Frasser

Software Engineer
Harris Snyder

Harris Snyder

Scientific Computing Engineer
Jay Yoo

Jay Yoo

Scientific Developer Intern
Michael McLean

Michael McLean

Scientific Developer Intern

Marcus Brubaker, PhD

Co-Founder & Scientific Advisor, ML and Computer Vision

John Rubinstein, PhD

Scientific Advisor, Cryo-EM

David Fleet, PhD

Scientific Advisor, ML and Computer Vision

Careers

We are looking for talented individuals to join our growing team. Send us an email at careers@structura.bio to let us know what you can bring to the team.

Full Stack Developer

Toronto, Canada

Contact

For general inquiries, please email info@structura.bio.

Blog

Visit the cryoSPARC Blog for feature updates and cryo-EM news.