Unlocking the potential of cryo-EM

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Structura builds software that enables fast, accurate and automated cryo-EM for drug discovery and research. We work closely with pharmaceutical companies and research labs globally.

Get the most out of your cryo-EM data with cryoSPARC™

CryoSPARC™ is the state-of-the-art platform used globally for obtaining 3D structural information from single particle cryo-electron microscopy (cryo-EM) data. The cryoSPARC™ platform enables automated, high quality and high-throughput structure discovery of proteins, viruses and molecular complexes for research and drug discovery.

Learn more about cryoSPARC™ for structural biology and drug discovery
Solve structures without any guesswork

Discover unexpected structures and conformational states directly from the data. The patent-pending algorithms underlying cryoSPARC™ enable rapid heterogeneous reconstructions without the need for prior structural knowledge.

Near-atomic resolution results

Obtain the highest resolution results in minutes using cryoSPARC™’s patent-pending refinement algorithms.

Special tools for high-value targets

Use cryoSPARC™’s specially designed algorithms to discover the structure of membrane proteins, ion channels, GPCRs, and targets with ligands bound.

Our Team

Ali Punjani
Co-Founder & CEO
Saara Punjani
Chief Operations Officer
Suhail Dawood
Chief Product Officer
Stephan Arulthasan
Software Engineer
Ali Haydaroglu
Research Consultant
Jay Yoo
Scientific Developer
Marcus Brubaker, PhD
Co-Founder and Expert Advisor, ML and Computer Vision
John Rubinstein, PhD
Expert Advisor, Cryo-EM
David Fleet, PhD
Expert Advisor, ML and Computer Vision


Structura Biotechnology Inc. is a Toronto-based startup affiliated with the University of Toronto.

We build computer vision and machine learning algorithms and software solutions to enhance the success of structural biology research and drug discovery projects. Our core technology enables research scientists and pharmaceutical companies to discover and understand the detailed three-dimensional structure of important protein molecules, complexes, and drug targets.

We are looking for talented individuals to join our growing team. Structura is the right fit for you if you are excited about solving complex problems, innovating into uncharted territory, and becoming an integral part of a team of motivated peers working to create something useful and meaningful.

Send us an email at to let us know what you can bring to the team.


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